14-3-3ζ (also known as tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3ζ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis (1). 14-3-3ζ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1 (2). 14-3-3ζ Protein is ideal for investigators involved in Cell Stress& Chaperone Proteins, Cell Signaling, AKT/PKB Pathway, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, WNT Signaling research.
序列
该【干冰】14-3-3 zeta recombinant protein - 009-001-R28的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】14-3-3 zeta recombinant protein - 009-001-R28的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】14-3-3 zeta recombinant protein - 009-001-R28的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.