ALK7 is a type I receptor for the TGFB family of signaling molecules in which type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (1). Alk7 was expressed in all insulin, glucagon, and somatostatin -positive cells of the pancreas (2). GDF3 regulates adipose tissue homeostasis and energy balance under nutrient overload, in part, by signaling through ALK7 and Alk7 showed reduced fat accumulation and partial resistance to diet-induced obesity, similar to Gdf3. ALK7 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, AKT/PKB Pathway, Angiogenesis, Cancer, Cardiovascular Disease, JAK/STAT Pathway, Neurobiology, and Ser/Thr Kinase research.
序列
该【干冰】ALK7 recombinant protein-GST fusion protein - 009-001-R39的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】ALK7 recombinant protein-GST fusion protein - 009-001-R39的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】ALK7 recombinant protein-GST fusion protein - 009-001-R39的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.