DLK or mitogen-activated protein kinase kinase kinase 12 is a transmembrane protein containing six epidermal growth factor repeats and is a serine/threonine protein kinase. DLK is involved in the differentiation of several cell types, including adipocytes. DLK plays a role of a tumor suppressor protein and is predominately expressed in neuronal cells. DLK as an activator of the Jnk pathway. Overexpression of DLK results in activation of Jnk1 and the accumulation of a hyperphosphorylated form of c-Jun (1). Postnatal loss of DLK in stem cells and niche astrocytes has been shown to regulate neurogenesis (2). DLK Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, and Ser/Thr Kinases research.
序列
该【干冰】DLK recombinant protein-GST fusion protein - 009-001-R84S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】DLK recombinant protein-GST fusion protein - 009-001-R84S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】DLK recombinant protein-GST fusion protein - 009-001-R84S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.