LOXL2 is a member of the lysyl oxidase gene family which is essential for the biogenesis of connective tissue. LOXL2 encodes an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. LOXL2 may play an important role in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family (1). LOXL2 may mediate fibroblast activation through enzymatic crosslinking of fibrillar collagen and local matrix tention, resulting in activation of TGFb1 signaling (2). LOXL2 Protein is ideal for investigators involved in Signaling Proteins, Lysyl Oxidase Proteins, Cancer, and Metabolic Disorder research.
序列
该【干冰】LOXL2 recombinant protein-GST fusion protein - 009-001-S41的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】LOXL2 recombinant protein-GST fusion protein - 009-001-S41的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】LOXL2 recombinant protein-GST fusion protein - 009-001-S41的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.