【干冰】Rel B recombinant protein-HIS Epitope - 009-001-T18S-【干冰】Rel B recombinant protein-HIS Epitope - 009-001-T18S代理/参数/厂家-重组蛋白-开云·官方站线上登录平台入口

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重组蛋白

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背景资料: Rel B is part of the NFkB complex and forms heterodimeric complexes with p50 (NFKB1) and p52 (NFKB2) (1). The homodimeric complexes of Rel B alone do not show DNA-binding activity. IHC analysis has shown that Rel B expression correlated with dendritic cell activation. NFkB-inducing kinase NIK is required for osteoclastogenesis in response to pathologic stimuli and overexpression of Rel B rescues differentiation of mouse NIK -/- osteoclast precursors. Rel B is required for RANKL-induced osteoclastogenesis in vitro and for TNF -induced bone resorption in vivo. This indicates that the alternative NFkB pathway, via Rel B, plays an essential and unique role in RANKL signaling toward osteoclast development (2). Rel B Protein is ideal for investigators involved in Signaling Proteins, Transcription Proteins, Apoptosis/Autophagy, Cancer, Inflammation, Neurobiology, and NFkB Pathway research.

序列: 该【干冰】Rel B recombinant protein-HIS Epitope - 009-001-T18S的详细信息查看Rockland提供的产品说明书。

来源宿主: 该【干冰】Rel B recombinant protein-HIS Epitope - 009-001-T18S的详细信息查看Rockland提供的产品说明书。

溶解建议: 该【干冰】Rel B recombinant protein-HIS Epitope - 009-001-T18S的详细信息查看Rockland提供的产品说明书。

保存建议: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。