中文名称

【干冰】SETDB2 recombinant protein-GST fusion protein - 009-001-T29

英文名字

【干冰】SETDB2 recombinant protein-GST fusion protein - 009-001-T29

供应商

Rockland

产品货号

009-001-T29

产品报价

￥询价/50ug

产品说明书

购买方式

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产品新闻

背景资料

SETDB2 is a histone H3 methyltransferase that modulates gene expression epigenetically through histone H3 methylation. Methylation of histone H3 at lysine 9 (H3K9) by SETDB2 has emerged as an important player in the formation of heterochromatin, chromatin condensation, and transcriptional repression. SETDB2 is recruited to heterochromatin regions and contributes in vivo to the deposition of trimethyl marks. Depletion of SETDB2 coincides with a loss of CENP proteins and delayed mitosis, suggesting that SETDB2 participates in chromosome condensation and segregation (1). Using positional cloning approach, SETDB2 has been cloned from a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma (2). SETDB2 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.

序列

该【干冰】SETDB2 recombinant protein-GST fusion protein - 009-001-T29的详细信息查看Rockland提供的产品说明书。

来源宿主

该【干冰】SETDB2 recombinant protein-GST fusion protein - 009-001-T29的详细信息查看Rockland提供的产品说明书。

溶解建议

该【干冰】SETDB2 recombinant protein-GST fusion protein - 009-001-T29的详细信息查看Rockland提供的产品说明书。

保存建议

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他

Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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