中文名称

【干冰】SMAD3 recombinant protein-GST fusion protein - 009-001-T39S

英文名字

【干冰】SMAD3 recombinant protein-GST fusion protein - 009-001-T39S

供应商

Rockland

产品货号

009-001-T39S

产品报价

￥询价/20ug

产品说明书

购买方式

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产品新闻

背景资料

SMAD3 is a direct mediator of transcriptional activation by the TGFβ receptor. The activity of SMAD3 is regulated by the TGFβ receptors, and SMAD3 is phosphorylated and associated with the ligand-bound receptor complex. TGFβ stimulation leads to phosphorylation and activation of SMAD3, which form a complex with SMAD4 that accumulate in the nucleus and regulate transcription of target genes such as CDK inhibitor (1). SMAD3 containing a C-terminal truncation acts as a dominant-negative inhibitor of the normal TGFβ response. SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2 (2). SMAD3 Protein is ideal for investigators involved in Signaling Proteins, Transcription Proteins, AKT/PKB Pathway, Angiogenesis, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, NfkB Pathway, and WNT Signaling research.

序列

该【干冰】SMAD3 recombinant protein-GST fusion protein - 009-001-T39S的详细信息查看Rockland提供的产品说明书。

来源宿主

该【干冰】SMAD3 recombinant protein-GST fusion protein - 009-001-T39S的详细信息查看Rockland提供的产品说明书。

溶解建议

该【干冰】SMAD3 recombinant protein-GST fusion protein - 009-001-T39S的详细信息查看Rockland提供的产品说明书。

保存建议

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他

Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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