LKB1 (STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly maintaining energy homeostasis in hematopoietic cells through a novel metabolic checkpoint (1). STK11 serves as an essential regulator of HSCs and hematopoiesis, and more generally, points to the critical importance of coupling energy metabolism and stem cell homeostasis (2). SKT11 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, and Ser/Thr Kinases research.
序列
该【干冰】STK11 recombinant protein-GST fusion protein - 009-001-T60的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】STK11 recombinant protein-GST fusion protein - 009-001-T60的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】STK11 recombinant protein-GST fusion protein - 009-001-T60的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.