【干冰】KDM4B recombinant protein-GST fusion protein - 010-001-S34-【干冰】KDM4B recombinant protein-GST fusion protein - 010-001-S34代理/参数/厂家-重组蛋白-开云·官方站线上登录平台入口

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重组蛋白

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背景资料: KDM4B or lysine (K)-specific demethylase 4B, which is also known as JMJD2B, contains a JmjN domain, a JmjC domain, a JD2H domain, 2 TUDOR domains, and a bipartite nuclear localization signal that overlaps the C-terminal part of the second TUDOR domain. KDM4B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6 (1). KDM4B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development (2). KDM4B is regulated by both ERa and HIF-1a, drives breast cancer cell proliferation in normoxia and hypoxia, and epigenetically regulates the expression of cell cycle genes such as CCND1, CCNA1, and WEE1. KDM4B Protein is ideal for investigators involved in Signaling Proteins, Deacetylase/Demethylase Proteins, Cancer, Cell Cycle, and Inflammation research.

序列: 该【干冰】KDM4B recombinant protein-GST fusion protein - 010-001-S34的详细信息查看Rockland提供的产品说明书。

来源宿主: 该【干冰】KDM4B recombinant protein-GST fusion protein - 010-001-S34的详细信息查看Rockland提供的产品说明书。

溶解建议: 该【干冰】KDM4B recombinant protein-GST fusion protein - 010-001-S34的详细信息查看Rockland提供的产品说明书。

保存建议: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。