T-2 toxin is a common trichothecene mycotoxin produced by Fusarium species, which can infect grain crops causing alimentary toxic aleukia in humans and animals. It triggers a ribotoxic response through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs, interferes with the metabolism of membrane phospholipids, and increases liver lipid peroxides.1 T-2 toxin is highly cytotoxic to macrophages, inducing apoptosis in primary porcine alveolar macrophage cells with an IC50 value of 19.47 nM. At 3 nM it decreases the production of inflammatory mediators (IL-1B, TNFa, and nitric oxide), TLR4, and TLR2/6 agonists.2Appearance:White SolidPurity:≥98%Melting Point:140-143°CStorage:-20˚C FreezerSolubility:Cyclohexane (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)