LTB4, Leukotriene B4 Lipid Maps MS Standard, 5S,12R-dihydroxy-6Z,8E,1E,14Z-eicosatetraenoic acid
供应商
Cayman
产品货号
10007240-500
产品报价
¥27552/500 ug
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产品新闻
背景资料
Leukotriene B4 -LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar ranges -3.9 x 10^-10 M), LTB4 causes chemotaxis and chemokinesis in human polymorphonuclear leukocytes. At higher concentrations, -1.0 x 10^-7 M), LTB4 leads to neutrophil aggregation and degranulation as well as superoxide anion production.