Ins(3,4,5,6)-P4|3,4,5,6-IP4, D-myo-Inositol-3,4,5,6-tetraphosphate -sodium salt), D-myo-inositol-3,4,5,6-tetra(hydrogen phosphate), tetrasodium salt
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Cayman
产品货号
10007782-5
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¥53900/5 mg
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背景资料
D-myo-Inositol-3,4,5,6-tetraphosphate -sodium salt) -Ins-3,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. It almost completely inhibits calcium-activated chloride channels at a concentration of 8-10 uM. Related inositol oligophosphates Ins-1,3,4,5)-P4, Ins-1,3,4,6)-P4, Ins-1,4,5,6)-P4, and Ins-1,3,4,5,6)-P5 do not inhibit the calcium channel at concentrations up to 100 uM. Ins-1,3,4)P3-mediated inhibition of Ins-3,4,5,6)-P4 1-kinase increases the cellular level of Ins-3,4,5,6)-P4, thus regulating channel inhibition. Ins-3,4,5,6)-P4 was found to be inactive when analyzed for Ca2+-releasing potency in Xenopus oocytes.
产品描述
D-myo-Inositol-3,4,5,6-tetraphosphate -sodium salt) -Ins-3,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. It almost completely inhibits calcium-activated chloride channels at a concentration of 8-10 uM.{13730} Related inositol oligophosphates Ins-1,3,4,5)-P4, Ins-1,3,4,6)-P4, Ins-1,4,5,6)-P4, and Ins-1,3,4,5,6)-P5 do not inhibit the calcium channel at concentrations up to 100 uM.{13730} Ins-1,3,4)P3-mediated inhibition of Ins-3,4,5,6)-P4 1-kinase increases the cellular level of Ins-3,4,5,6)-P4, thus regulating channel inhibition.{8674} Ins-3,4,5,6)-P4 was found to be inactive when analyzed for Ca2+-releasing potency in Xenopus oocytes.{13725}