Ins(1,4,5,6)-P4|1,4,5,6-IP4, D-myo-Inositol-1,4,5,6-tetraphosphate -sodium salt), D-myo-inositol-1,4,5,6-tetra(hydrogen phosphate), tetrasodium salt
供应商
Cayman
产品货号
10007783-5
产品报价
¥53900/5 mg
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背景资料
D-myo-Inositol-1,4,5,6-tetraphosphate -sodium salt) -Ins-1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins-1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella. Ins-1,4,5,6)-P4 antagonizes epidermal growth factor -EGF) signalling through the phosphatidylinositol 3-kinase pathway. Ins-1,4,5,6)-P4 -tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins-1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
产品描述
Ins-1,4,5,6)-P4 is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins-1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.{13729} Ins-1,4,5,6)-P4 antagonizes epidermal growth factor -EGF) signalling through the phosphatidylinositol 3-kinase pathway.{13729} Ins-1,4,5,6)-P4 -tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins-1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.{13725}