8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation. It inhibits cyclooxygenase -IC50 = 14 uM), human 12-lipoxygenase -IC50 = 0.46 uM), 5-lipoxygenase -IC50 = 25 uM) and the actions of slow-reacting substance of anaphylaxis -SRS-A) -IC50 = 10 uM).
产品描述
8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation.{14705} It inhibits cyclooxygenase -IC50 = 14 uM), human 12-lipoxygenase -IC50 = 0.46 uM), 5-lipoxygenase -IC50 = 25 uM) and the actions of slow-reacting substance of anaphylaxis -SRS-A) -IC50 = 10 uM).{14704,14706}