中文名称

8-iso Prostaglandin E2-d4 (500 ug)

英文名字

8-iso PGE2-d4|8-epi PGE2-d4, 8-iso Prostaglandin E2-d4, 9-oxo-11.alpha.,15S-dihydroxy-(8.beta.)-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid

供应商

Cayman

产品货号

10011321-500

产品报价

￥27104/500 ug

产品说明书

购买方式

产品新闻

背景资料

8-iso Prostaglandin E2-d4 -8-iso PGE2-d4) contains four deuterium atoms at the hydroxyethyl 3, 3 ,4, and 4 positions. It is intended for use as an internal standard for the quantification of 8-iso PGE2 by GC- or LC-mass spectrometry. 8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 uM, respectively. When infused into the renal artery of the rat at a concentration of 4 mg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.

产品描述

An internal standard for the quantification of 8-iso PGE2 by GC- or LC-MS

产品形式

保存建议

-20

其他

Cayman Chemical

注意

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