Anti-Human MMP-7-Anti-Human MMP-7代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: Matrix metalloproteinases (MMPs) are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP7 (matrilysin) is expressed in epithelial cells of normal and diseased tissues, and is capable of digesting a large series of proteins of the extracellular matrix including collagen IV and X, gelatin, casein, laminin, aggrecan, entactin, elastin and versican. MMP7 is implicated in the activation of other proteinases such as plasminogen, MMP1, MMP2, and MMP9. In addition to its roles in connective tissue remodeling and cancer, MMP7 also regulates intestinal α-defensin activation in innate host defense, releases tumor necrosis factorα in a model of herniated disc resorption, and cleaves FasL to generate a soluble form in a model of prostate involution. Structurally, MMP7 is the smallest of the MMPs and consists of two domains: a prodomain that is cleaved upon activation and a catalytic domain containing the zincbinding site.

保存建议: 该Anti-Human MMP-7的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

其他: ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。