Anti-Human MMP-14-Anti-Human MMP-14代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

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背景资料: As the first member of membrane type (MT) MMPs, MMP-14, also known as MT1MMP, plays an important role in extracellular matrix (ECM) remodeling by being able to degrade type I collagen, activate pro MMP2 and process cell adhesion molecules such as CD44 and integrin αV. MMP-14 is therefore a key enzyme in many physiological and pathological processes such as angiogenesis and tumor invasion. Structurally, MMP14 consists of the following domains: a pro domain containing the furin cleavage site, a catalytic domain containing the zinc binding site, a hinge region, a hemopexin-like domain, a transmembrane domain, and a cytoplamasic tail. Recombinant Human MMP-14 consists of the pro and catalytic domains, which can be activated by treatment with furin.

保存建议: 该Anti-Human MMP-14的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

其他: ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。