IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
应用类型
WB, IHC (F), N
免疫原
该Anti-Human IL-1 alpha的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human IL-1 alpha的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human IL-1 alpha的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human IL-1 alpha的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.