ULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells.
应用类型
WB
免疫原
该Anti-Human ULBP-3的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human ULBP-3的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human ULBP-3的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human ULBP-3的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.