13-epi-12-oxo Phytodienoic acid -13-epi-12-oxo PDA) is a lipoxygenase metabolite of .alpha.-linolenic acid in the leaves of green plants such as corn. .omega.-3 and .omega.-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases. 12-oxo PDA is one of the best studied end metabolites of this enzymatic pathway. While the initial enzymatic product and major isomer of 12-oxo PDA contains side chains in the cis position, both being .beta. to the ring, the upper side chain attached at C-13, can and frequently does, isomerize when 12-oxo PDA is extracted, isolated, or stored. 13-epi-12-oxo PDA is the product of this isomerization.
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13-epi-12-oxo PDA is an LO metabolite of .alpha.-linolenic acid in the leaves of green plants such as corn. .omega.-3 and .omega.-6 PUFAs in plants are substrates for plant LOs.{857} 12-oxo PDA is one of the best studied end metabolites of this enzymatic pathway.{1562} While the initial enzymatic product and major isomer of 12-oxo PDA contains side chains in the cis position, both being .beta. to the ring, the upper side chain attached at C-13, can and frequently does, isomerize when 12-oxo PDA is extracted, isolated, or stored. 13-epi-12-oxo PDA is the product of this isomerization.