Resiniferatoxin is a natural analog of capsaicin (Item No. 92350) isolated from some plants of the genus Euphorbia, including E. resinifera.{24788,24789} It activates the transient receptor potential cation channel subfamily V member 1 (TrpV1), formerly known as vanilloid receptor 1, with a Ki value of 20 pM.{24790} It is an extremely potent and selective activator of a sub-population of primary afferent neurons.{24787,24791}
产品描述
A natural analog of capsaicin that activates TrpV1 with a Ki value of 20 pM; potently and selectively activates of a sub-population of primary afferent neurons