中文名称

Metformin (10 g)

英文名字

Biguanide|Cidophage|DMGG|Glucofine, Metformin, N,N-dimethyl-imidodicarbonimidic diamide

供应商

Cayman

产品货号

11965-10

产品报价

￥2128/10 g

产品说明书

购买方式

产品新闻

背景资料

Metformin is a biguanide compound which lowers blood glucose concentrations in patients with type 2 diabetes. It activates AMP-activated protein kinase -AMPK) in primary hepatocytes when given at 500 uM, resulting in decreased glucose production. Activation of AMPK also increase the expression of the nuclear receptor SHP in liver cells, which inhibits the expression of the gluconeogenic genes PEPCK and glucose-6-phosphatase. Metformin can have different effects on AMPK activity in other types of cells and can signal through AMPK-independent pathways. Metformin may also be useful in the prevention and treatment of cancer.

产品描述

A biguanide compound which lowers blood glucose concentrations in patients with type 2 diabetes; AMPK in primary hepatocytes when given at 500 uM, which inhibits glucose production; may also be useful in the prevention and treatment of cancer

产品形式

保存建议

22

其他

Cayman Chemical

注意

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