中文名称

人纤维蛋白原（250mg）

英文名字

Fibrinogen (human)

供应商

Cayman Chemical

产品货号

16088-250

产品报价

￥已停产

产品说明书

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购买方式

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产品新闻

背景资料

Fibrinogen is a large 340 kDa multimeric plasma glycoprotein involved in blood clotting. It is composed of two sets of three different polypeptide chains (α, β, and r subunits) held together by 29 disulfide bonds.{26114} The six fibrinogen chains are assembled such that the amino terminal ends of all the subunits gather at the central core. Two globular domains are held together by three polypeptide chains that form a long coiled-coil structure.{26116} The α and β chains of fibrinogen contain sequences called the fibrinopeptide sequences, which prevent fibrinogen from spontaneously polymerizing.{26113} Conversion of fibrinogen into insoluble fibrin strands is catalyzed by the serine protease thrombin (Item No. 13188) during blood clot formation. Thrombin catalyses the rapid release of fibrinopeptide A and then fibrinopeptide B after a lag phase. The fibrin monomers then spontaneously polymerize to form an insoluble gel. The polymerized fibrin is stabilized by noncovalent and electrostatic interactions promoted by factor XIIIa. Factor XIII, also known as fibrin stabilizing factor, is a transglutaminase that is activated by thrombin. The aggregated insoluble fibrin along with platelets are responsible for blocking damaged blood vessels during blood clotting.{26113}

产品描述

提供的人纤维蛋白原（250mg）产品形式为：A lyophilized powder containing ~15% sodium citrate and ~25% sodium chloride.

产品形式

Fibrinogen is a large 340 kDa multimeric plasma glycoprotein involved in blood clotting. It is composed of two sets of three different polypeptide chains (��, ��, and r subunits) held together by 29 disulfide bonds.{26114} The six fibrinogen chains are assembled such that the amino terminal ends of all the subunits gather at the central core. Two globular domains are held together by three polypeptide chains that form a long coiled-coil structure.{26116} The �� and �� chains of fibrinogen contain sequences called the fibrinopeptide sequences, which prevent fibrinogen from spontaneously polymerizing.{26113} Conversion of fibrinogen into insoluble fibrin strands is catalyzed by the serine protease thrombin (Item No. 13188) during blood clot formation. Thrombin catalyses the rapid release of fibrinopeptide A and then fibrinopeptide B after a lag phase. The fibrin monomers then spontaneously polymerize to form an insoluble gel. The polymerized fibrin is stabilized by noncovalent and electrostatic interactions promoted by factor XIIIa. Factor XIII, also known as fibrin stabilizing factor, is a transglutaminase that is activated by thrombin. The aggregated insoluble fibrin along with platelets are responsible for blocking damaged blood vessels during blood clotting.{26113}

保存建议

建议您在收到Cayman Chemical品牌的人纤维蛋白原（250mg）产品后置于-80度保存，产品有效期为730天.

其他

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，开云·官方站线上登录平台入口_开云(中国) 将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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