Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit-Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit代理/参数/厂家-细胞分析试剂盒-开云·官方站线上登录平台入口

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细胞分析试剂盒

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中文名称: Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit

英文名字: Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit

供应商: USBiological

产品货号: 169632

产品报价: ￥1/1Kit

产品说明书

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产品新闻

背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: Calpain 1 is calcium-dependent, non-lysosomal cysteine protease with low calcium requirement. It is expressed ubiquitously and in the brain, mainly localized to the cell body and dendrites of neurons and to a lesser extent in axons and glial cells. Hyperactivation of calpains is implicated in a number of pathologies associated with altered calcium homeostasis such as Alzheimer's disease as well as secondary degeneration resulting from acute cellular stress following cerebral (neuronal) ischemia, traumatic brain injury and spinal cord injury.Intended Use:The kit provides a rapid, simple, sensitive, and reliable test suitable for high throughput screening of Calpain 1 inhibitors. Inhibitor control (Calpain inhibitor 1, ALLN) is included to compare the efficacy of test inhibitors.Test Principle:Human calpain 1 inhibitor screening kit is based on the detection of cleavage of calpain substrate Ac-LLY-AFC. Ac-LLY-AFC possess very weak fluorescence; upon cleavage of the substrate by calpain 1, free AFC can be quantified fluorometrically (Ex/Em = 400/505nm). In the presence of potent Calpain 1 inhibitor, the hydrolyzation of substrate will be impeded.Specificity:MammalianKit Components:Assay buffer, 1x25mlSubstrate, 1x0.2mlCalpain 1 Enzyme, 1x0.2mlInhibitor Control (1um), 1x0.5mlStorage and Stability:Store powder at 4°C, liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

产品特点: 针对Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit该产品的特点优势，欢迎查阅官网提供的产品说明书。

保存建议: 建议收到Calpain 1 Inhibitor, Human, Fluorometric, Screening BioAssay Kit产品后将其置于-70°C保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。