Cyclooxygenase (COX)-1 and -2, also called prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) are key regulatory enzymes in the PG biosynthetic pathway. COX enzymes catalyze the committed step in the conversion of arachidonic acid to PGH2 (Item No. 17020). These enyzmes are the major targets for NSAIDs that are used to reduce pain, inflammation, and fever.{8931}
产品描述
Recombinant protein expressed in Sf21 cells using the Baculovirus system • One unit is defined as the amount of enzyme required to consume 1 nmol of oxygen per minute 37°C in 100 mM Tris, pH 8.0, containing 100 µM arachidonate, 5 mM EDTA, 2 mM phenol, and 1 µM hematin.
产品形式
Cyclooxygenase (COX)-1 and -2, also called prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) are key regulatory enzymes in the PG biosynthetic pathway. COX enzymes catalyze the committed step in the conversion of arachidonic acid to PGH2 (Item No. 17020). These enyzmes are the major targets for NSAIDs that are used to reduce pain, inflammation, and fever.{8931}