Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. This antibody is suitable for researchers interested in cell research and cytoskeletal signaling research.
应用类型
ELISA,Immunohistochemistry,Western Blot,
免疫原
Gelsolin antibody was produced in mice by repeated immunizations with human plasma gelsolin.
来源宿主
Mouse
反应性
H. sapiens (Human); Leporidae (Rabbit)
保存建议
Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.