Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy.
CPN10 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the c-terminal region of human Cpn10 synthetic peptide.
来源宿主
Rabbit
反应性
Bovine (Bos Taurus); Canine (Dog); Cavia porcellus (Guinea Pig); H. sapiens (Human); Leporidae (Rabbit); Mus musculus (Mouse); Ovis aries (Sheep); Rattus (Rat); Sus scrofa domesticus (Pig, Porcine, Swine); Xenopus
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.