【干冰】Anti-Nur77 (RABBIT) Antibody - 200-401-H99-【干冰】Anti-Nur77 (RABBIT) Antibody - 200-401-H99代理/参数/厂家-一抗-开云·官方站线上登录平台入口

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一抗

开云·官方站线上登录平台入口_开云(中国)

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背景资料: Anti Nur7 antibody detects human Nur77. Nur77 (Nak-1,TR3) is a member of the NR4A orphan nuclear receptor (NR) superfamily of transcription factors. The Nur77 ligand has not yet been identified. It is thought that the lack of ability to identify a ligand may be due to the lack of a typical NR binding pocket in the ligand binding domain. Nur77, like other NR4A receptors, are immediate-early genes induced by diverse stimuli in multiple tissues. There is increasing evidence that Nur77 and other NR4A receptors play important roles in maintaining tissue homeostasis. For example, specific Nur77 functions have been defined in the brain, T-cells/thymocytes, adipose tissue, steroidgenesis, muscle, blood vessels, macrophages and cardiovascular system. There is also evidence that Nur77 plays roles in pathological processes such as cancer. Nur77 is a phosphoprotein and its size ranges from ~65 kDa to 90 kDa depending on the isoform expressed and level of phosphorylation or other post-translational modifications. Anti-Nur77 antibody is ideal for investigators involved in apoptosis.

免疫原: Nur77 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to internal amino acids with human Nur77 protein.

保存建议: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。