This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). The AGAPs are the largest subgroup of the ArfGAP family with 11 genes in humans. AGAP4 (also known as Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4) is a GTPase activating protein. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. AGAP4 and other AGAP proteins likely function in the secretory pathway, which could explain a link with the invasive behavior of cancer cells. Reliable antibodies would be invaluable for studies of the physiologic function of the proteins and how is may be linked to cancer cell invasive behavior. Anti-AGAP4 Antibody is useful for researchers interested in Developmental Biology, apoptosis, Cancer, Immunology, and Nuclear Signaling research.
应用类型
ELISA,Western Blot,
免疫原
Anti-AGAP4 antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant His-tagged AGAP4 protein.
来源宿主
Rabbit
反应性
H. sapiens (Human)
保存建议
Store antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.