Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)-Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)代理/参数/厂家-细胞分析试剂盒-开云·官方站线上登录平台入口

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中文名称: Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)

英文名字: Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)

供应商: USBiological

产品货号: 207352

产品报价: ￥1/96Tests

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背景资料: USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！

产品描述: Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer‘s disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.Sample Type:Cell culture supernatant, plasma, serumIntended Use:The human Progranulin BioAssay ELISA Kit is to be used for the in vitro quantitative determination of human progranulin in serum, plasma, urine, cell culture supernatant and cerebrospinal fluid (CSF; R. Ghidoni et al.; Neurology 71: 1235 (2008)). Sensitivity:32pg/mlRange:0.063-4ng/mlSpecificity:Recognizes human progranulin.Test Principle:This BioAssay is a sandwich Enzyme Linked-Immunosorbent Assay (ELISA) for quantitative determination of human progranulin in biological fluids. A polyclonal antibody specific for progranulin has been precoated onto the 96-well microtiter plate. Standards and samples are pipetted into the wells for binding to the coated antibody. After extensive washing to remove unbound compounds, progranulin is recognized by the addition of a biotinylated polyclonal antibody specific for progranulin (Detection Antibody). After removal of excess biotinylated antibody, HRP labeled streptavidin (Detector) is added. Following a final washing, peroxidase activity is quantified using the substrate 3,3’,5,5’-tetramethylbenzidine (TMB). The intensity of the color reaction is measured at 450nm after acidification and is directly proportional to the concentration of progranulin in the samples.Kit Components:Plate coated with human progranulin antibody, 1x96wellsWash Buffer 10X, 1x50mlDiluent 5X, 1x50mlDetection Antibody, 1x12mlDetector 100X (HRP Labeled Streptavidin), 1x150ulHuman progranulin Standard, lyophilized, 1x8ngHuman progranulin QC sample, lyophilized, 1x vialTMB Substrate Solution, 1x12mlStop Solution, 1x12mlPlate sealers, 3x plastic filmStorage and Stability:Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

产品特点: 针对Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)该产品的特点优势，欢迎查阅官网提供的产品说明书。

保存建议: 建议收到Progranulin, Human, BioAssay ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)产品后将其置于4°C/-20°C保存。

其他: Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。