BRCA1 Antibody,BRCA1,BRCA-1,breast cancer 1,breast and ovarian cancer susceptibility protein 1,RNF53,Ring Finger 53,IRIS,PSCP.
供应商
Biovision
产品货号
3364-100
产品报价
¥已停产
产品说明书
购买方式
银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868.
产品新闻
背景资料
BRCA1 is a breast cancer susceptibility gene that was localized to chromosome 17q. Mutations within this gene are believed to account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues,including breast and ovary,and encodes a predicted protein of 1863 amino acids. Like many other genes involved in familial cancer,BRCA1 appears to encode a tumor suppressor,a protein that acts as a negative regulator of tumor growth.
应用类型
Western blotting (1-4 ug/ml), immunoprecipitation (10-20 ug/ml), and Immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 1852 of human BRCA1