Stat5抗体-Stat5 Antibody，Signal transducer and activator of transcription 5，stat -5，STAT5，STAT-5，STAT 5代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: Stat5 Antibody，Signal transducer and activator of transcription 5，stat -5，STAT5，STAT-5，STAT 5

背景资料: Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6，it has been shown that Stat3B appears to be activated by both while Stat3 is activated by EGF，but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

应用类型: Western blotting （2-10 ug/ml）， immunoprecipitation （20 ug/ml） and Immunohistochemistry （20 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~95 kDa Stat5 of human， mouse and rat origins. Reactivity to other species has not been tested.

保存建议: 提供的Stat5抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于的PBS缓冲液中.请将该Stat5抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

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