磷酸化Stat6抗体-Phospho-Stat6 Antibody，STAT6B，STAT6C，D12S1644，IL-4-STAT，interleukin 4 induced STAT代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: Phospho-Stat6 Antibody，STAT6B，STAT6C，D12S1644，IL-4-STAT，interleukin 4 induced STAT

背景资料: Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6，it has been shown that Stat3B appears to be activated by both while Stat3 is activated by EGF，but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

应用类型: Western blotting （1-4 ug/ml） and Immunohistochemistry （20 ug/ml）. However， the optimal concentrations should be determined individually.

免疫原: Synthetic phospho-peptide corresponding to resides surrounding Tyr641 of human Stat6

保存建议: 提供的Phospho-Stat6抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02% 叠氮钠 The antibody recognizes ~110 kDa phosphorylated Stat6 （Tyr641） of human和mouse origins. Reactivity to other species has not been tested. 的PBS缓冲液中.请将该Phospho-Stat6抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

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