磷酸BRCA1抗体-Phospho-BRCA1 Antibody，BRCA1，BRCA pSer 1280，Breast Cancer Gene 1，Breast Cancer 1，Early Onset； Breast-Ovarian Cancer Susceptibility代理/参数/厂家-二抗-开云·官方站线上登录平台入口

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二抗

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英文名字: Phospho-BRCA1 Antibody，BRCA1，BRCA pSer 1280，Breast Cancer Gene 1，Breast Cancer 1，Early Onset； Breast-Ovarian Cancer Susceptibility

背景资料: BRCA1 is a breast cancer susceptibility gene that was localized to chromosome 17q. Mutations within this gene are believed to account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues，including breast and ovary，and encodes a predicted protein of 1863 amino acids. Like many other genes involved in familial cancer，BRCA1 appears to encode a tumor suppressor，a protein that acts as a negative regulator of tumor growth.

应用类型: Western blotting （1-2 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been tested yet. Detect human BRCA1 when phosphorylated at Ser1189.

免疫原: Phosphorylated synthetic peptide surrounding Serine 1189 of human BRCA1

保存建议: 提供的Phospho-BRCA1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Phospho-BRCA1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

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