PAK1 Antibody (p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK, p65-PAK )
供应商
Biovision
产品货号
3908-100
产品报价
¥已停产
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产品新闻
背景资料
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase,PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase,and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.