IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.
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重组人白介素-17E蛋白产品,又称Interleukin 17E,Interleukin-25, .其对应NCBI基因号为3605,NCBI基因别称为IL17;该基因种属来源为人源,对应Accession号为Q16552 .该蛋白产品又称Human IL-17E, IL-17E, IL 17E, IL 17E, h-IL-17E, rh-IL-17E, recombinant human IL-17E, recombinant IL-17, IL-17, interluekin-17等.