RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
序列
重组人RANTES蛋白产品,又称Small inducible cytokine A5, CCL5, T-cell-specific RANTES protein, SIS-delta, T cell- specific protein P228, TCP228, chemokine (C-C motif) ligand 5, SISd, SCYA5, RANTES, D17S136E, MGC17164. .其对应NCBI基因号为6352,对应Accession号为P13501.
来源宿主
提供的【RANTES】重组人RANTES产品的来源为大肠杆菌重组表达.
溶解建议
重组人RANTES产品请按照说明书建议进行溶解操作:Reconstitute in H₂O to a concentration of 0.1-1 ug/ul. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°c for future use. .