BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. Recombinant human BMP-2 is a 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains
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重组人骨形态发生蛋白-2蛋白产品,又称BMP-2, BMP2A, bone morphogenetic protein2.其对应NCBI基因号为10220,NCBI基因别称为BMP11/GDF11;该基因种属来源为人源,对应Accession号为O95390.该蛋白产品又称human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP等.