BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-10 is essential for the proper development of the heart, but is not expressed until after cardiac patterning or looping are completed. Recombinant human BMP-10 is a 32 kDa disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
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重组人骨形态发生蛋白-10蛋白产品,又称bone morphogenetic protein 10, BMP10, BMP 10.其对应NCBI基因号为8200,NCBI基因别称为GDF5;该基因种属来源为人源,对应Accession号为X80915.该蛋白产品又称BMP-10, BMP10, BMP 10等.