中文名称

【NRG 1】再生人神经调节蛋白/Heregulin-1β（NRG-1β/HRG-1β）（10 ug）

英文名字

Neuregulin/Heregulin-1β (NRG-1β/HRG-1β), human recombinant

供应商

Biovision

产品货号

4711-10

产品报价

￥已停产

产品说明书

购买方式

银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.

产品新闻

背景资料

Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extraCellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulin-β1 (65 amino acid residues).

序列

重组人Neuregulin/Heregulin-1β (NRG-1β/HRG-1β)蛋白产品，又称NGR beta 1, Heregulin, HRG 1beta, Neuregulin, Neuregulin1 (NRG1-β1), Neu differentiation factor, Pro-neuregulin-1, Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory and motor neuron-derived factor .其对应NCBI基因号为3084，对应Accession号为P08311.

来源宿主

提供的【NRG 1】重组人Neuregulin/Heregulin-1β (NRG-1β/HRG-1β)产品的来源为大肠杆菌重组表达.

溶解建议

重组人Neuregulin/Heregulin-1β (NRG-1β/HRG-1β)产品请按照说明书建议进行溶解操作：Reconstitute in H₂O to a concentration of 0.1-1.0 ug/ul. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. .

保存建议

在您收到艾美捷发出的【NRG 1】重组人Neuregulin/Heregulin-1β (NRG-1β/HRG-1β)产品后，建议将其置于-20°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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