Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 218 amino acid residues.
序列
重组人胰岛素样生长因子-BP1蛋白产品,又称IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.其对应NCBI基因号为3484,对应Accession号为P08833.
来源宿主
提供的【IGF BP1】重组人胰岛素样生长因子-BP1产品的来源为Nso细胞重组表达.
溶解建议
重组人胰岛素样生长因子-BP1产品请按照说明书建议进行溶解操作:Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. .