Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors. Recombinant mouse follistatin is a nonglycosylated protein, containing 289 amino acids, with a molecular weight of 31.6 kDa.
序列
重组小鼠卵泡抑素蛋白产品,又称FS, activin-binding protein, FSH-suppressing protein (FSP).其对应NCBI基因号为14313,对应Accession号为P47931.
来源宿主
提供的【Follistatin】重组小鼠卵泡抑素产品的来源为大肠杆菌重组表达.
溶解建议
重组小鼠卵泡抑素产品请按照说明书建议进行溶解操作:Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.