中文名称

【Serpin E1】重组人Serpin E1 / PAI-1（1000 ug）

英文名字

Serpin E1/PAI-1, human recombinant

供应商

Biovision

产品货号

4731-1000

产品报价

￥已停产

产品说明书

购买方式

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产品新闻

背景资料

Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SERPINE1 and PLANH1, is a secreted protein which belongs to the serpin family. SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SERPINE1 defect in the plasma. High concentrations of SERPINE1 have been associated with thrombophilia which is an autosomal dominant disorder in which affected individuals are prone to develop serious spontaneous thrombosis.

序列

重组人Serpin E1/PAI-1蛋白产品，又称Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1).其对应NCBI基因号为5054，对应Accession号为P05121.

来源宿主

提供的【Serpin E1】重组人Serpin E1/PAI-1产品的来源为人细胞重组表达.

溶解建议

重组人Serpin E1/PAI-1产品请按照说明书建议进行溶解操作：It is recommended to reconstitute the lyophilized Recombinant Human SERPIN E1 in PBS not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

保存建议

在您收到艾美捷发出的【Serpin E1】重组人Serpin E1/PAI-1产品后，建议将其置于-70°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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