D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.
序列
重组人D4-GDI蛋白蛋白产品,又称D4-GDI, D4GDI, Rho GDP dissociation inhibitor (GDI) α.其对应NCBI基因号为12308,NCBI基因别称为Calb2;该基因种属来源为小鼠源,对应Accession号为Q08331.该蛋白产品又称D4-GDI, D4GDI, Rho GDP dissociation inhibitor (GDI) alpha等.
来源宿主
提供的【D4 GDI】重组人D4-GDI蛋白产品的来源为大肠杆菌中重组表达.
溶解建议
提供的重组人D4-GDI蛋白 产品为液态形式以100 ug/ml浓度溶解于50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20%甘油的无菌过滤溶液中.