Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. HepatoCellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18. The recombinant human keratin-8 is expressed in E. coli and purified by proprietary chromatographic techniques.
序列
重组人细胞角蛋白8蛋白产品,又称Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2, .其对应NCBI基因号为396,NCBI基因别称为ARHGDIA ;该基因种属来源为人源,对应Accession号为NM_004309.该蛋白产品又称Ke大鼠in type II cytoskeletal 8, Cytoke大鼠in-8, CK-8, Ke大鼠in-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2, 等.
来源宿主
提供的【Keratin 8】重组人细胞角蛋白8产品的来源为大肠杆菌中重组表达.
溶解建议
提供的重组人细胞角蛋白8 产品为液态形式以5 ug/50 ul浓度溶解于50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20%甘油的无菌过滤溶液中.