Prolactin is a pituitary hormone that plays a role in the stimulation of milk production, salt and H₂O regulation, growth, development and reproduction. The primary step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin is a hormone involved in a range of significant functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. Prolactin exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane Prolactin receptor. PRLR varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. Recombinant human Prolactin Receptor (Extra Cellular Domain) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 210 amino acids and having a molecular mass of 23.97 kDa.
序列
重组人催乳激素受体蛋白产品,又称PRL-R, hPRLrI, PRL, luteotropic hormone, LTH, PRLR, PRL-R, PRL R .其对应NCBI基因号为5618,对应Accession号为P16471.
来源宿主
提供的【Prolactin Receptor】重组人催乳激素受体产品的来源为大肠杆菌重组表达.
溶解建议
重组人催乳激素受体产品请按照说明书建议进行溶解操作:Reconstitute in sterile dH₂O to a concentration of 0.1 -1 mg/ml and let the lyophilized pellet dissolve completely. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. .