APBA1 Antibody (NT) (Amyloid beta 4 (A4) precursor protein-binding family A member 1, X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA)
供应商
Biovision
产品货号
5280-100
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer’s disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the AB peptide that is deposited in the brains of Alzheimer’s disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK,a multidomain scaffolding protein involved in brain development and synapse formation.
应用类型
Western Blot: 0.5 - 1 ug/ml, ELISA. However, the optimal conditions should be determined individually.
免疫原
APBA1 antibody was raised against a 19 amino acid peptide near the amino terminus of human APBA1.