TGF-beta Receptor I Antibody,Transforming growth factor beta receptor I,TGFR1,TGFR-1,TGFR 1,TGF beta receptor type 1,TbetaR I,Serine/threonine-protein kinase receptor R4,SKR4,SKR 4
供应商
Biovision
产品货号
5636R-100
产品报价
¥已停产
产品说明书
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产品新闻
背景资料
TGF-B (Transforming growth factor-beta superfamily members are critical regulators of cell proliferation,differentiation,morphogenesis,and pathogenesis. TGF-beta receptor is a serine/threonine kinase receptor complex that consists of two distinct transmembrane proteins known as type I and type II receptors. In response to ligand binding,the type II receptors form a stable complex with the type I receptors allowing phosphorylation and thus activation of the type I receptor kinases.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. antibody detects 30 and 55 kDa isoforms of TGF-B Receptor I on SDS-PAGE immunoblots in samples from human, mouse, rat, pig and bovine origins.
免疫原
Synthetic peptide surrounding amino acid 411 of human TGF-B Receptor I