BMP-4 Antibody,BMP4,BMP-4,BMP 4,bone morphogenetic protein 4,BMP2B,BMP2B1
供应商
Biovision
产品货号
5674R-100
产品报价
¥已停产
产品说明书
购买方式
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产品新闻
背景资料
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name,BMPs initiate,promote and regulate bone development,growth,remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B),suggesting that BMP-4 may play a role in activation of the Smad pathway.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide surrounding amino acid 395 of human BMP-4
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠、鸡、兔种属来源的BMP-4蛋白发生免疫反应.
保存建议
提供的BMP-4抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该BMP-4抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.