p38, also called SAPK2A, belongs to the MAP kinase family. The MAP kinases are critical signaling proteins for many biochemical signals. They participate in transcription regulation, cellular differentiation and proliferation. Environmental signals and cytokines catalyze the kinases into bonding their substrates such as MAX and ATF2, for example, and p53 a tumor suppressing gene. p38 may be associated with diseases such as chlamydia and patellar tendinitis. Anti-p38 antibody is useful for researchers interested in signal pathways, cellular development or cancer research.
Anti-p38 antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human p38 conjugated to Keyhole Limpet Hemocyanin (KLH).
来源宿主
Goat
反应性
H. sapiens (Human); Mus musculus (Mouse)
保存建议
Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.